Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents
Authors
McCormack SE, Shaham O, McCarthy MA et al
Journal
Pediatric Obesity
Abstract
Objective
To determine whether paediatric obesity is associated with elevations in fasting circulating concentrations of BCAAs (isoleucine, leucine and valine), and whether these elevations predict future insulin resistance.
Conclusions
Elevations in the concentrations of circulating BCAAs are significantly associated with obesity in children and adolescents, and may independently predict future insulin resistance.
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